How can the virion be killed outside the human body ?

How can the virion be killed outside the human body ?

Virions, which are individual virus particles, can be inactivated or "killed" outside the human body through various methods. It's important to note that different viruses may have varying levels of susceptibility to these methods. For the SARS-CoV-2 virus responsible for COVID-19, common methods to inactivate virions include:

  1. Soap and Detergent: Soap and detergents disrupt the lipid membrane that surrounds the virus, causing it to break apart and become inactive. Washing surfaces or hands with soap and water is an effective way to remove and kill the virus.

  2. Alcohol-Based Disinfectants: Alcohol-based hand sanitizers with at least 60% alcohol content can effectively kill many types of viruses, including coronaviruses. These sanitizers break down the protein coat of the virus and disrupt its structure.

  3. Bleach: A diluted bleach solution (usually 1 part bleach to 9 parts water) can effectively inactivate viruses on surfaces. Bleach disrupts the viral proteins and nucleic acids, rendering the virus inactive.

  4. Hydrogen Peroxide: Hydrogen peroxide is another disinfectant that can be used to kill viruses. It works by damaging the viral proteins and genetic material.

  5. UV Radiation: Ultraviolet (UV) radiation, particularly UVC light, can damage the genetic material of viruses and prevent them from replicating. UV light is used in some disinfection processes for surfaces and air.

  6. Heat: Elevated temperatures, such as those achieved through steam cleaning or high-temperature laundering, can denature the proteins of viruses and render them non-infectious.

  7. Quaternary Ammonium Compounds: These are commonly used disinfectants in household and commercial settings. They can disrupt the lipid membrane of the virus, leading to its inactivation.

It's important to follow proper guidelines and instructions for using these methods to ensure effective disinfection and safety. Different surfaces and materials might require different methods of disinfection, and the effectiveness of each method can depend on factors such as concentration, contact time, and the specific virus being targeted.


The SARS-CoV-2 virion can be killed outside the human body by a variety of methods. These include:

  • Ultraviolet (UV) light: UV light can damage the virion's RNA, making it unable to replicate.
  • Heat: Heat can also damage the virion's RNA. For example, the virion is inactivated within 1 minute at 56°C (133°F).
  • Chemical disinfectants: There are a number of chemical disinfectants that can kill the SARS-CoV-2 virion. These include bleach, alcohol, and hydrogen peroxide.
  • Soap and water: Soap and water can also help to kill the SARS-CoV-2 virion. This is because soap helps to break down the virion's lipid envelope.

It is important to note that the virion can survive for some time on surfaces. For example, it can survive for up to 72 hours on cardboard and up to 4 hours on copper. Therefore, it is important to clean and disinfect surfaces regularly, especially if they have been touched by someone who is sick.

Here are some additional tips for killing the SARS-CoV-2 virion outside the human body:

  • Wash your hands often with soap and water for at least 20 seconds.
  • Avoid touching your eyes, nose, and mouth.
  • Cover your mouth and nose with a tissue when you cough or sneeze.
  • Dispose of tissues in a closed trash can.
  • Clean and disinfect surfaces regularly.
  • Stay home if you are sick.

By following these tips, you can help to protect yourself and others from the SARS-CoV-2 virus.